What are the symptoms of endometriosis?
A common symptom of endometriosis is pain, mostly in
the abdomen, lower back, and pelvic areas. The
amount of pain a woman feels is not associated with
the extent of endometriosis. Some women have no
pain even though their disease affects large areas, or
there is significant scarring. Some women, on the
other hand, have severe pain even though they have
only a few small areas of visible endometriosis.
General Symptoms can include (but are not limited
to):
Extremely painful (or disabling) menstrual
cramps; pain may get worse over time
Chronic pelvic pain (includes lower back pain
and pelvic pain)
Pain during sex (dyspareunia)
Intestinal pain
Painful bowel movements or painful urination
during menstrual periods
Heavy menstrual periods
Premenstrual spotting or bleeding between pe-
riods
Infertility (can’t get pregnant)
Endometriosis can, also, be associated with Irrita-
ble Bowel Syndrome and Interstitial Cystitis.
How is Endometriosis Diagnosed?
A History and Physical exam performed by a knowl-
edgeable Gynecologist is important. Your doctor may
then recommend an ultrasound and possibly an MRI.
These are tests often performed by a Radiologist.
The only way to know for sure, however, is to have
laparoscopy. This surgery is performed with general
anesthesia and involves inserting a telescope through
you belly button. Usually endometriosis can be diag-
nosed (with a biopsy) and treated in the same laparo-
scopic surgery.
What causes endometriosis?
No one knows for sure what causes this disease.
The two plausible theories include retrograde men-
strual flow (menses backs up through the fallopian
tubes into the abdomen) and genetics. Clearly endo-
metriosis “runs in families”.
Researchers, also, are looking at the role of the im-
mune system and how it either stimulates or reacts to
endometriosis. It may be that a woman’s immune
system does not remove the menstrual fluid in the
pelvic cavity properly, or the chemicals made by en-
dometriosis may irritate or promote growth of more
areas. Women who have endometriosis are more
likely to have other auto-immune diseases such as
fibromyalgia, eczema, etc.
Other research is focusing on hormonal impact on
endometriosis. Still further research is looking at
chemical markers. This could help diagnose endo-
metriosis without surgery. In addition, it would allow a
doctor to follow the success of treatments.
What is the treatment for endometriosis?
There is no cure for endometriosis (it is a chronic dis-
ease). But there are many treatments, each of which
has pros and cons. It is important to build a good
relationship with your doctor, so you can decide what
option is best for you.
Pain medication: For some women with mild
symptoms, no further treatment other than medi-
cation for pain may be needed. For women with
minimal endometriosis who want to become preg-
nant, doctors are saying that, depending on the
age of the woman and her amount of pain from
the disease, the best thing to do is to have a trial
period of unprotected sex for six months to one
year. Further treatment may be necessary if
pregnancy doesn’t occur.
Hormone Treatment: There are several hor-
mones used for treatment including BCP (birth
control pills), progesterone pills, Danazol (a weak
male hormone), GnRH agonist (gonadotropin
releasing hormone.
...
dedicated to healthy lifestyles and safe, state-of-the-art, innovative surgery for women of all ages
Birth Control Pills: Usually contain two hor-
mones, estrogen and progesterone. BCPs often
control the growth of the tissue that lines the
uterus and in the same way controls endome-
triosis tissue. BCPs can be taken cyclically (you
will have a menstrual cycle) or continuously (you
likely will not have a menstrual cycle). If a
woman can’t take estrogen then she can take
progesterone only pills or Danazol. All medi-
cines have side effects and for these they in-
clude: weight gain, abnormal bleeding, bloating,
blood clots in the legs, and rarely heart attack
and stroke (usually if used in unhealthy women
who smoke).
Danazol has become more popular than pro-
gesterone only because it may improve PMS
and also significantly reduce the menstrual flow.
The side effects may be oily skin, acne, weight
gain, muscle cramps, headaches, dizziness,
and deepening of the voice.
GnRH Agonist: is a once a month or every
three months injection that prevent ovarian hor-
mone production. As a result a woman doesn’t
have a period and therefore the growth of endo-
metriosis is slowed or stopped. These medica-
tions simulate a temporary menopausal state
and can cause hot flushes, insomnia, mood
swings, memory and concentration loss, possi-
ble bone loss. Usually a person stays on this
medication for 6 months. Usually this medicine
controls the pain of endometriosis which recurs
after the medicine is stopped.
Surgery
It is now believed that surgery combined with
medical therapy is the best combination to have
the greatest success in managing endometriosis
and its symptoms. Surgery is most often per-
formed by Laparoscopy. Endometriosis is ex-
cised and sent for pathologic evaluation. Sur-
gery may be conservative in most cases but
sometimes a woman may elect to remove her
uterus, tubes, and ovaries. This, too, can be
done with laparoscopy.
Women with endometriosis often feel sadness,
fear, anger, confusion, and alone. There is sup-
port available. Talk with your provider.
Raymond Wayne Whitted MD, MPH